Molecular Pathology & Genomics

Bat swarming and immunity

Bats carry some of the deadliest zoonotic diseases that can infect both humans and animals, such as Ebola and COVID-19.

Fibroblast cells and pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, it is claimed.

Pores for thought

A team from Nottingham looks at intraoperative molecular diagnosis of brain tumours using nanopore sequencing.

Activating genes using CRISPR technology

There are over 7000 different rare genetic diseases, and often it can be a significant challenge and take a long time to receive a correct diagnosis.

The search for genes that cause diseases

A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease.

Figuring out the threats: Problem-solving with genomics

As the COVID-19 enquiry continues to unpick the tangled threads of the pandemic response, little has been said about one of the most effective weapons against the SARS-Cov-2 virus – pathogen genomics.

Breast cancer cells’ self-sacrifice is potential cause of relapse

For patients with early-stage breast cancer, there is a 7% to 11% chance of relapse within five years after receiving initial treatment.

Specialist diploma in molecular pathology

On behalf of the members of the Molecular Pathology Advisory Panel, Chair Dr Andrew Blann introduces the new Specialist Diploma.

The role of organelle repair in fighting infection

Research has found that cellular structures act as “molecular plasters” that protect against infections, such as tuberculosis. We talk to study co-author Claudio Bussi.

Early-stage stem cell therapy trial

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

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